New tests improve in vitro fertilization
Updated: 2013-07-24 21:35
By Chen Hong and Li Yifei (chinadaily.com.cn)
|
||||||||
Scientists in Shenzhen said they have applied a new genome sequencing method to detect genetic defects among in vitro fertilized embryos, which can lead to a higher chance of having healthy babies for couples who suffer infertility.
The first baby screened with the new method - who was born in Hunan province on Aug 24, 2012, weighing 2.4 kg - is now at normal development, BGI Shenzhen announced at a news conference on Monday.
Scientists removed seven to 12 cells from morphologically normal human embryos five days after fertilization in vitro for preimplantation sequencing. Then they used the latest DNA technologies to detect abnormalities, which will determine the genetically intact embryos.
“The preimplantation sequencing may have a crucial role in improving the efficiency and safety of human assisted reproduction,” said Du Yutao, vice-president of BGI Health Group.
Gabor Vajta, a professor from the University of Copenhagen, said the discovery can bring the success rate of pregnancies from 50-55 percent to around 60-70 percent.
Nearly 5 million babies have been born using in vitro fertilization since the birth of world's first test-tube baby in 1978.
In recent years, new-generation sequencing has been widely used in stem cell transplant and metastatic tumor cells, mainly associated with the improvements of human health, according to BGI.
“The new-generation sequencing method shows significant accuracy enhancement over other existing screening techniques in identifying abnormalities in embryos, which allows doctors to only implant a healthy lab-fertilized egg in the womb,” said Lu Guangxiu, president of Reproductive and Genetic Hospital of Citic-Xiangya, which cooperated with BGI.
According to BGI, Citic-Xiangya transferred sequenced embryos for 33 couples and has achieved 22 pregnancies since 2010. The success rate stood at 66.7 percent. So far, 17 healthy babies have been born.
- Yuan: Financial capitals vying for top spot
- Little princes and princesses
- Obama lauds Louisville in White House visit
- PLA special forces hold military contest
- Weiner not dropping out of NYC mayoral race
- Kate and William show off Britain's new prince
- Summer heat brings surge in patients
- Sansha welcomes new hospital
Most Viewed
Editor's Picks
Safety worries mount |
Giving ancient Lhasa a facelift |
Families feel the pull of 'gravity' |
Party seeks to boost ties with the public |
Conundrum over sexual bribery |
Bar street heaven for expats, hell for locals |
Today's Top News
Royals keep world waiting for baby's name
Chinese vice president to visit DPRK
Guangzhou to launch 72-hour visa-free stays
US diplomat says China ties a priority
Pharma corruption crackdown widens
US still top choice for students
NFL makes cyber play in China
Nation falling short on IT security
US Weekly
Geared to go |
The place to be |